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Cover Feature: On the Metal Cooperativity in a Dinuclear Copper–Guanidine Complex for Aliphatic C−H Bond Cleavage by Dioxygen (Chem. Eur. J. 48/2019)
Author(s) -
Schön Florian,
Biebl Florian,
Greb Lutz,
Leingang Simone,
GrimmLebsanft Benjamin,
Teubner Melissa,
Buchenau Sören,
Kaifer Elisabeth,
Rübhausen Michael A.,
Himmel HansJörg
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201902620
Subject(s) - guanidine , chemistry , copper , hydroxylation , cooperativity , bond cleavage , metal , cleavage (geology) , stereochemistry , polymer chemistry , photochemistry , enzyme , catalysis , organic chemistry , materials science , biochemistry , fracture (geology) , composite material
Metal cooperativity in a binuclear copper–guanidine complex enables aliphatic hydroxylation as known from the enzyme α‐hydroxylating monooxygenase (PHM). In the model complex reported, one copper atom is responsible for dioxygen activation, whereas the role of the second copper atom is to stabilize the product after C−H bond cleavage. Related mononuclear copper complexes, which do not profit from this cooperative effect, display no hydroxylation activity. More information can be found in the Full Paper by H.‐J. Himmel et al. on page 11257.