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The Effect of Branching on the One‐ and Two‐Photon Absorption, Cell Viability, and Localization of Cationic Triarylborane Chromophores with Dipolar versus Octupolar Charge Distributions for Cellular Imaging
Author(s) -
Griesbeck Stefanie,
Michail Evripidis,
Rauch Florian,
Ogasawara Hiroaki,
Wang Chenguang,
Sato Yoshikatsu,
Edkins Robert M.,
Zhang Zuolun,
Taki Masayasu,
Lambert Christoph,
Yamaguchi Shigehiro,
Marder Todd B.
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201902461
Subject(s) - chromophore , photochemistry , two photon absorption , triphenylamine , cationic polymerization , dipole , fluorescence , chemistry , absorption (acoustics) , excited state , acceptor , optics , organic chemistry , physics , atomic physics , laser , condensed matter physics
Two different chromophores, namely a dipolar and an octupolar system, were prepared and their linear and nonlinear optical properties as well as their bioimaging capabilities were compared. Both contain triphenylamine as the donor and a triarylborane as the acceptor, the latter modified with cationic trimethylammonio groups to provide solubility in aqueous media. The octupolar system exhibits a much higher two‐photon brightness, and also better cell viability and enhanced selectivity for lysosomes compared with the dipolar chromophore. Furthermore, both dyes were applied in two‐photon excited fluorescence (TPEF) live‐cell imaging.