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Cover Feature: A Three‐Color Fluorescent Supramolecular Nanoassembly of Phototherapeutics Activable by Two‐Photon Excitation with Near‐Infrared Light (Chem. Eur. J. 29/2019)
Author(s) -
Fraix Aurore,
Kirejev Vladimir,
Malanga Milo,
Fenyvesi Éva,
Béni Szabolcs,
Ericson Marica B.,
Sortino Salvatore
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201901550
Subject(s) - fluorescence , singlet oxygen , supramolecular chemistry , photochemistry , chemistry , supramolecular polymers , materials science , optics , organic chemistry , oxygen , molecule , physics
A supramolecular nanoassembly based on a fluorescein‐labeled β‐cyclodextrin branched polymer co‐encapsulating two different guests can be excited in the therapeutic window with two near‐infrared (NIR) photons, permitting the simultaneous activation of five distinct functionalities, such as the generation of green, red, and blue fluorescence for bioimaging, and the cytotoxic singlet oxygen and nitric oxide for bimodal therapeutic effects. More information can be found in the Communication by M. B. Ericson, S. Sortino et al. on page 7091.