Batch and Continuous‐Flow Iron(II)‐Catalyzed Synthesis of Sulfilimines and Sulfoximines using  N ‐Mesyloxycarbamates | Zendy

Lai Calvine | Zendy; Mathieu Gary | Zendy; Gabrielli Tabarez Lucia Paola | Zendy; Lebel Hélène | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Batch and Continuous‐Flow Iron(II)‐Catalyzed Synthesis of Sulfilimines and Sulfoximines using N ‐Mesyloxycarbamates

Author(s) -

Lai Calvine,

Mathieu Gary,

Gabrielli Tabarez Lucia Paola,

Lebel Hélène

Publication year - 2019

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201900953

Subject(s) - amination , catalysis , continuous flow , chemistry , combinatorial chemistry , homogeneous , hydrate , base (topology) , chemical engineering , organic chemistry , thermodynamics , mathematics , biochemical engineering , engineering , physics , mathematical analysis

The synthesis of sulfilimines and sulfoximines with N ‐mesyloxycarbamates in presence of catalytic iron(II) chloride hydrate is described. The use of 1‐butylimidazole as a base proved instrumental in enabling a homogeneous reaction mixture compatible with continuous flow processes. The amination is applicable to a wide range of substrates, and affords the desired product in good to excellent yields within 1 to 60 minutes.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research