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Nickel‐Copper‐Catalyzed Hydroacylation of Vinylarenes with Acyl Fluorides and Hydrosilanes
Author(s) -
Ueda Yusuke,
Iwai Tomohiro,
Sawamura Masaya
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201900822
Subject(s) - hydroacylation , copper , nickel , catalysis , chemistry , organic chemistry , rhodium
The hydroacylation of vinylarenes with acyl fluorides and hydrosilanes was enabled by a synergistic bimetallic Ni/Cu‐catalytic system, giving access to the corresponding branched ketone products. The reaction takes place under mild conditions at 25–80 °C and tolerates base‐sensitive functional groups such as methoxycarbonyl and acetoxy groups.
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