Synthesis of Functionalized Ketones from Acid Chlorides and Organolithiums by Extremely Fast Micromixing | Zendy

Nagaki Aiichiro | Zendy; Sasatsuki Kengo | Zendy; Ishiuchi Satoshi | Zendy; Miuchi Nobuyuki | Zendy; Takumi Masahiro | Zendy; Yoshida Junichi | Zendy

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Synthesis of Functionalized Ketones from Acid Chlorides and Organolithiums by Extremely Fast Micromixing

Author(s) -

Nagaki Aiichiro,

Sasatsuki Kengo,

Ishiuchi Satoshi,

Miuchi Nobuyuki,

Takumi Masahiro,

Yoshida Junichi

Publication year - 2019

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201900743

Subject(s) - micromixing , chemoselectivity , microreactor , electrophile , chemistry , combinatorial chemistry , mixing (physics) , functional group , organic chemistry , catalysis , polymer , analytical chemistry (journal) , physics , quantum mechanics

Synthesis of ketones containing various functional groups from acid chlorides bearing electrophilic functional groups and functionalized organolithiums was achieved using a flow microreactor system. Extremely fast mixing is important for high chemoselectivity.

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