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Front Cover: Protonation and Anion Binding Properties of Aromatic Bis‐Urea Derivatives—Comprehending the Proton Transfer (Chem. Eur. J. 18/2019)
Author(s) -
Barišić Dajana,
Cindro Nikola,
Kulcsár Marina Juribašić,
Tireli Martina,
Užarević Krunoslav,
Bregović Nikola,
Tomišić Vladislav
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201900674
Subject(s) - protonation , chemistry , proton , ion , urea , ligand (biochemistry) , aromaticity , front cover , medicinal chemistry , computational chemistry , cover (algebra) , combinatorial chemistry , inorganic chemistry , molecule , organic chemistry , receptor , mechanical engineering , physics , quantum mechanics , engineering , biochemistry
A study of aromatic bis‐urea derivatives in DMSO revealed their unexpectedly high acidity (p K a ≈14). Consequently, partial proton transfer occurs in their reaction with basic anions (AcO − and H 2 PO 4 − ). This process was quantitatively accounted for in the course of anion‐binding studies. Reliable stability constants of anion complexes (1:1 and 1:2, receptor:anion) were determined. Factors defining the anion‐binding properties of the studied ligand series are thoroughly discussed. More information can be found in the Full Paper by N. Bregović et al. on page 4695.