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Phosphazene Base t Bu‐P4 Catalyzed Methoxy–Alkoxy Exchange Reaction on (Hetero)Arenes
Author(s) -
Shigeno Masanori,
Hayashi Kazutoshi,
NozawaKumada Kanako,
Kondo Yoshinori
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201900498
Subject(s) - chemistry , phosphazene , superbase , alkoxy group , catalysis , intramolecular force , medicinal chemistry , citronellol , base (topology) , organic chemistry , ring (chemistry) , menthol , alkyl , mathematical analysis , polymer , mathematics , chromatography , essential oil , geraniol
Abstract The organic superbase t Bu‐P4 catalyzes methoxy‐alkoxy exchange reactions on (hetero)arenes with alcohols. The catalytic reaction proceeded efficiently with electron‐deficient methoxy(hetero)arenes as well as with a variety of alcohols, including 3‐amino‐1‐propanol, β‐citronellol, menthol, and cholesterol. An intramolecular version of this reaction furnished six‐ and seven‐membered ring compounds.