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Frontispiece: Ruthenium‐Crosslinked Hydrogels with Rapid, Visible‐Light Degradation
Author(s) -
Rapp Teresa L.,
Highley Christopher B.,
Manor Brian C.,
Burdick Jason A.,
Dmochowski Ivan J.
Publication year - 2018
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201881064
Subject(s) - self healing hydrogels , ruthenium , degradation (telecommunications) , drug delivery , visible spectrum , irradiation , materials science , in vivo , nanotechnology , chemistry , biophysics , computer science , polymer chemistry , optoelectronics , telecommunications , catalysis , organic chemistry , physics , microbiology and biotechnology , nuclear physics , biology
Light‐responsive hydrogels show promise in targeted drug delivery, as they can load and deliver sensitive cargo when triggered. To make these hydrogels more amenable for use in vivo, I. J. Dmochowski and colleagues have used a nontoxic ruthenium‐based crosslinker to form a hydrogel that degrades upon irradiation with visible light, releasing an active protein cargo. For the full story see the Communication on page 2328 ff.