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Rh III ‐Catalyzed Straightforward Synthesis of Benzophenanthroline and Benzophenanthrolinone Derivatives using Anthranils
Author(s) -
Biswas Aniruddha,
Sarkar Souradip,
Samanta Rajarshi
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201806373
Subject(s) - amination , quinoline , annulation , catalysis , chemistry , indole test , combinatorial chemistry , enantioselective synthesis , conjugated system , organic chemistry , polymer
An efficient pot‐economic and step‐economic Rh III ‐catalyzed site‐selective direct amination/annulation strategy was developed for the synthesis of benzophenanthroline derivatives using quinoline N‐oxides and anthranils. The method was further extended to the synthesis of nitrogen‐containing extended π‐conjugated benzophenanthrolinone derivatives. Late‐stage functionalizations of cinchonidine and cinchophen derivatives and synthesis of a bioactive quinolino‐indole were achieved.