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Cover Feature: A Hexavalent Basket for Bottom‐Up Construction of Functional Soft Materials and Polyvalent Drugs through a “Click” Reaction (Chem. Eur. J. 5/2019)
Author(s) -
Neal Taylor A.,
Wang Weikun,
Zhiquan Lei,
Peng Ruojing,
Soni Priti,
Xie Han,
Badjić Jovica D.
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201806120
Subject(s) - cavitand , combinatorial chemistry , click chemistry , chemistry , cover (algebra) , feature (linguistics) , molecule , nanotechnology , computer science , materials science , organic chemistry , supramolecular chemistry , engineering , linguistics , philosophy , mechanical engineering
A dual‐cavity host , with six terminal alkynes at the periphery of its two fused cavitands, is obtained at the gram scale by following straightforward synthetic protocols. This structurally unique and multivalent cavitand can be efficiently clicked to carbohydrates, polymers, or small functional molecules. The stage is thus set for exploring the preparation of novel multivalent drugs and nanostructured soft materials. More information can be found in the Full Paper by J. D. Badjić et al. on page 1242.