z-logo
Premium
Pd‐Catalyzed Annulation of 1‐Halo‐8‐arylnaphthalenes and Alkynes Leading to Heptagon‐Embedded Aromatic Systems
Author(s) -
Yan Jianming,
Rahman Md. Shafiqur,
Yoshikai Naohiko
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201805746
Subject(s) - annulation , fluoranthene , catalysis , chemistry , naphthalene , palladium , medicinal chemistry , organic chemistry , pyrene
A palladium‐catalyzed heptagon‐forming annulation reaction between 1‐halo‐8‐arylnaphthalene and diarylacetylene is reported. The reaction is promoted using a catalytic system comprised of Pd(OAc) 2 , moderately electron‐deficient triarylphosphine P(4‐ClC 6 H 4 ) 3 , and Ag 2 CO 3 to afford benzo[4,5]cyclohepta[1,2,3‐ de ]naphthalene derivatives in moderate to good yields, in preference to fluoranthene as a competing byproduct. Twofold annulation can also be achieved to access a novel heptagon‐embedded polycyclic aromatic hydrocarbon compound.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom