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A Closed Metallomolecular Cage that can Open its Aperture by Disulfide Exchange
Author(s) -
Akine Shigehisa,
Miyashita Masato,
Nabeshima Tatsuya
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201805359
Subject(s) - cage , disulfide bond , chemistry , ion , bridging (networking) , ion exchange , polymer chemistry , crystallography , combinatorial chemistry , organic chemistry , computer science , biochemistry , structural engineering , computer network , engineering
A closed metallomolecular cage based on the tris(saloph) framework, in which its aperture can be opened by disulfide exchange, was designed. At the apertures of the molecular cage, bridging diamine ligands having a disulfide bond were introduced to close the cage structure. These bridging ligands efficiently blocked the uptake of a guest, Cs + , but the presence of a thiolate anion significantly accelerated the guest uptake. This clearly means that this cage complex became open by the addition of the thiolate anion, because the cage closure becomes more dynamic due to the disulfide exchange reaction.