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Filling a Niche in “Ligand Space” with Bulky, Electron‐Poor Phosphorus(III) Alkoxides
Author(s) -
Hussein Sharifa,
Priester Denis,
Beet Paul,
Cottom Jonathon,
Hart Sam J.,
James Tim,
Thatcher Robert J.,
Whitwood Adrian C.,
Slattery John M.
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201804805
Subject(s) - steric effects , chemistry , organometallic chemistry , ligand (biochemistry) , alkoxide , coordination complex , electronic effect , stereochemistry , catalysis , combinatorial chemistry , crystallography , metal , organic chemistry , biochemistry , receptor
The chemistry of phosphorus(III) ligands, which are of key importance in coordination chemistry, organometallic chemistry and catalysis, is dominated by relatively electron‐rich species. Many of the electron‐poor P III ligands that are readily available have relatively small steric profiles. As such, there is a significant gap in “ligand space” where more sterically bulky, electron‐poor P III ligands are needed. This contribution discusses the coordination chemistry, steric and electronic properties of P III ligands bearing highly fluorinated alkoxide groups of the general form PR n (OR F ) 3− n , where R=Ph, R F =C(H)(CF 3 ) 2 and C(CF 3 ) 3 ; n= 1–3. These ligands are simple to synthesize and a range of experimental and theoretical methods suggest that their steric and electronic properties can be “tuned” by modification of their substituents, making them excellent candidates for large, electron‐poor ligands.