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Dehydrogenative Silylation of Alcohols Under Pd‐Nanoparticle Catalysis
Author(s) -
Pramanik Suman,
Fernandes Anthony,
Liautard Virginie,
Pucheault Mathieu,
Robert Frederic,
Landais Yannick
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201803989
Subject(s) - silylation , silanes , catalysis , chemistry , organic chemistry , primary (astronomy) , selectivity , combinatorial chemistry , silane , physics , astronomy
Pd‐nanoparticle‐catalyzed dehydrogenative coupling between various hydrosilanes and alcohols was shown to provide silyl ethers in good and reproducible yields. The synthetic methodology is effective for a wide range of simple and bulky silanes and secondary alcohols, while keeping various other functional groups intact. The procedure also exhibits high selectivity for the silylation of primary versus secondary alcohols in 1,2‐diols, and allows the successive silylation of alkynols and hydrogenation of the triple bond to afford Z ‐alkenols in good yields.