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Supermacrocyclic Assemblies by Hydrogen‐Bond Codes of C7‐Phenol Pyrazolo and Pyrrolo Derivatives of Adenine
Author(s) -
Chai Yingying,
Zhou Xinglong,
Li Changfu,
Ma Beibei,
Shen Zhen,
Huang Ridong,
Chen Hai,
Chen Bojiang,
Li Weimin,
He Yang
Publication year - 2018
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201803429
Subject(s) - hydrogen bond , phenol , chemistry , bond , combinatorial chemistry , medicinal chemistry , business , organic chemistry , molecule , finance
Abstract Hydrogen bond (HB) mediated base pair motifs are versatile scaffolds of diverse supramolecular constructs. Here, we report that two new four‐ and six‐membered supermacrocyclic assemblies with intriguing geometries could self‐assemble from two new adenine derivatives, APN ( 1 ) and APC ( 2 ). The conversion of a conventional HB acceptor, N8 of 1 , to a non‐conventional HB donor, C8−H of 2 , had a pronounced impact on the overall intricate HB network and self‐assembly patterns, epitomizing the subtleties in design and exploitation of such base‐pair motifs as promising tectons for building supramolecular architectures.