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Cover Feature: Photocontrol of Drug Release from Supramolecular Hydrogels with Green Light (Chem. Eur. J. 45/2018)
Author(s) -
Karcher Johannes,
Pianowski Zbigniew L.
Publication year - 2018
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201803349
Subject(s) - self healing hydrogels , supramolecular chemistry , photochromism , chemistry , green light , combinatorial chemistry , photochemistry , biophysics , polymer chemistry , materials science , blue light , organic chemistry , molecule , biology , optoelectronics
A photochromic cyclic dipeptide reversibly changes its molecular geometry upon alternate irradiation with green and violet light. Supramolecular hydrogels formed by one isomer dissipate to fluids when exposed on green light. The nontoxic gels encapsulate various cargo, including anticancer, antibiotic, or anti‐inflammatory drugs. The cargo can be released in the light‐controlled manner. We suppressed bacterial growth with green light using the gel loaded with ciprofloxacin. More information can be found in the Full Paper by Z. L. Pianowski and J. Karcher on page 11605.