Premium
Poly‐γ‐ p ‐Biphenylmethyl‐Glutamate as Enantiodifferentiating Alignment Medium for NMR Spectroscopy with Temperature‐Tunable Properties
Author(s) -
Jeziorowski Sharon,
Thiele Christina M.
Publication year - 2018
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201802921
Subject(s) - anisotropy , materials science , residual dipolar coupling , dipole , polymer , nuclear magnetic resonance spectroscopy , orientation (vector space) , spectroscopy , crystallography , chemistry , optics , stereochemistry , physics , organic chemistry , composite material , mathematics , geometry , quantum mechanics
Abstract The use of anisotropic NMR parameters—especially residual dipolar couplings (RDCs)—offers access to additional structural information and, therefore, alignment media required for this approach are under a continuous development. Here, we present poly‐γ‐ p ‐biphenylmethyl‐glutamate (PBPMG) as a new versatile enantiodifferentiating alignment medium. The thermoresponsive properties of this polymer allowed for RDC measurements of more than one orientation within the same sample at different temperatures. Moreover, the outstanding enantiodifferentiation along with excellent spectral quality even offered the opportunity to differentiate enantiomers in mixtures.