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N ‐Boc‐Amides in Cross‐Coupling Reactions
Author(s) -
BourneBranchu Yann,
Gosmini Corinne,
Danoun Grégory
Publication year - 2019
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201802635
Subject(s) - amide , electrophile , coupling reaction , chemistry , coupling (piping) , cross reactions , computational chemistry , combinatorial chemistry , organic chemistry , materials science , catalysis , biology , metallurgy , antibody , immunology
Since 2015, the use of amides as electrophilic partners in cross‐coupling reactions has experienced exponential growth. Diverse amide derivatives have been studied and among them N ‐Boc‐amides have shown good activities towards various cross‐coupling reactions and presents, in our view, an important synthetic usefulness. This review describes the recent developments of these chemical transformations involving N ‐Boc‐amides.