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Cover Feature: Pressure‐Induced Dissolution and Reentrant Formation of Condensed, Liquid–Liquid Phase‐Separated Elastomeric α‐Elastin (Chem. Eur. J. 33/2018)
Author(s) -
Cinar Hasan,
Cinar Süleyman,
Chan Hue Sun,
Winter Roland
Publication year - 2018
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201802505
Subject(s) - reentrancy , elastomer , phase (matter) , mesoscopic physics , dissolution , hydrostatic pressure , compartmentalization (fire protection) , materials science , chemical engineering , phase diagram , elastin , chemistry , polymer chemistry , thermodynamics , composite material , organic chemistry , physics , medicine , pathology , engineering , enzyme , condensed matter physics , quantum mechanics
Liquid–liquid phase separation appears to play an important role in the membraneless compartmentalization of cells and possibly also in the development of prebiotic cells, which might have evolved in the deep sea. This work shows how high hydrostatic pressures modify the mesoscopic structure of condensates comprised of α‐elastin. A novel pressure‐induced reentrant phase separation was observed in the intermediate temperature range. More information can be found in the Communication by R. Winter et al. on page 8286.