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Front Cover: A Magnetic Chameleon: Biocompatible Lanthanide Fluoride Nanoparticles with Magnetic Field Dependent Tunable Contrast Properties as a Versatile Contrast Agent for Low to Ultrahigh Field MRI and Optical Imaging in Biological Window (Chem. Eur. J. 29/2018)
Author(s) -
Biju Silvanose,
Gallo Juan,
BañobreLópez M.,
Manshian Bella B.,
Soenen Stefaan J.,
Himmelreich Uwe,
Vander Elst Luce,
ParacVogt Tatja.
Publication year - 2018
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201801814
Subject(s) - contrast (vision) , lanthanide , biocompatible material , materials science , nanoparticle , magnetic resonance imaging , excitation , core (optical fiber) , magnetic field , contrast ratio , nuclear magnetic resonance , nanotechnology , optoelectronics , optics , chemistry , biomedical engineering , physics , ion , medicine , organic chemistry , quantum mechanics , composite material , radiology
A new type of biocompatible multimodal contrast agent capable of enhancing the contrast of both magnetic resonance and optical images is reported. The nanoparticles, based on core‐shell lanthanide fluoride, show intense emission at 802 nm upon excitation with near infrared radiation. They also display magnetic field dependent contrasting properties and act as T 1 ‐weighted MRI contrast agents below 1.5 T, as T 1 / T 2 ‐dual weighted contrast agents at 3 T, and as highly efficient T 2 ‐weighted contrast agents at ultrahigh magnetic fields. More information can be found in the Full Paper by T. N. Parac‐Vogt et al. on page 7388.