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Acyl Radicals from Terminal Alkynes: Photoredox‐Catalyzed Acylation of Heteroarenes
Author(s) -
Sultan Shaista,
Rizvi Masood Ahmad,
Kumar Jaswant,
Shah Bhahwal Ali
Publication year - 2018
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201801628
Subject(s) - acylation , radical , regioselectivity , photoredox catalysis , chemistry , catalysis , photochemistry , combinatorial chemistry , organic chemistry , photocatalysis
A photoredox‐mediated acylation reaction of electron deficient heteroarenes with terminal alkynes is reported. The method relies on oxidative cleavage of phenylacetylenes for generation of acyl radicals as a key enabling feature. The reaction is regioselective with broad substrate scope. Quantum yield investigations support a radical chain mechanism.
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