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Frontispiece: Utilizing Palladium‐Stabilized Zwitterions for the Construction of N‐Heterocycles
Author(s) -
Allen Benjamin D. W.,
Lakeland Christopher P.,
Harrity Joseph P. A.
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201785662
Subject(s) - electrophile , palladium , nucleophile , selectivity , combinatorial chemistry , catalysis , chemistry , organic chemistry
Pd catalysis provides a convenient method for the generation of zwitterionic intermediates that offer significant opportunities for the synthesis of functionalized heterocycles. The combination of electrophilic π‐allyl Pd fragments and C‐, N‐ and O‐centered nucleophiles allows these intermediates to react with readily available substrates to furnish a range of high value products with control of chemo‐, regio‐ and stereo‐selectivity. For more details see the Review article by J. P. A. Harrity et al. on page 13830 ff.