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Frontispiece: Design of Organic Macrocycle‐Modified Iron Oxide Nanoparticles for Drug Delivery
Author(s) -
Skorjanc Tina,
Benyettou Farah,
Olsen JohnCarl,
Trabolsi Ali
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201783562
Subject(s) - iron oxide nanoparticles , drug delivery , nanoparticle , nanotechnology , drug , combinatorial chemistry , chemistry , oxide , targeted drug delivery , rational design , materials science , pharmacology , organic chemistry , medicine
Combining macrocycles and iron oxide nanoparticles (IONPs) is a rational strategy for creating drug delivery systems that target tumors, deliver potent anticancer agents, and effect thermal therapy. Macrocycles can be attached to IONPs either indirectly or directly. For a detailed discussion of different strategies for attaching macrocycles to IONPs as well as a look at different mechanisms for drug release see the Review by A. Trabolsi et al. on page 8333 ff.