Premium
Frontispiece: Borylative Radical Cyclizations of Benzo[3,4]cyclodec‐3‐ene‐1,5‐diynes and N‐Heterocyclic Carbene‐Boranes
Author(s) -
Watanabe Takashi,
Hirose Daisuke,
Curran Dennis P.,
Taniguchi Tsuyoshi
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201782362
Subject(s) - radical , carbene , boranes , chemistry , medicinal chemistry , photochemistry , stereochemistry , organic chemistry , boron , catalysis
Boryl radicals attack alkynes of strained diynes to induce subsequent radical cyclization. The image illustrates a radical chain reaction (the photo of space was taken by NASA). There are few examples of boryl radical addition to triple bonds, but the chemistry of N‐heterocyclic carbene–boranes realizes this rare transformation. The reaction is a new model for expanding utilization of boryl radicals to synthetic methods. More information can be found in the Communication by D. P. Curran, T. Taniguchi et al. on page 5404 ff.