Premium
Frontispiece: Gold‐Catalyzed Enantioselective Annulations
Author(s) -
Li Yangyan,
Li Wenbo,
Zhang Junliang
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201780361
Subject(s) - enantioselective synthesis , catalysis , chemistry , combinatorial chemistry , organic chemistry
Gold Catalysis Gold‐catalyzed enantioselective cycloadditions, cyclizations, cycloisomerizations, and tandem annulations are of great interest for rapid construction of optically active hetero‐ and carbocyclic molecules. In the Review on page 467 ff., J. Zhang et al. summarize the methods to construct chiral cyclic compounds by gold‐catalyzed enantioselective annulations reported during the last decade. There are four main general annulation types catalyzed by chiral gold complexes or chiral gold salts: cycloadditions, cyclizations of C−C multiple bonds with tethered nucleophiles, cycloisomerization or cyclization of enynes, and tandem annulations, which are all discussed alongside some other strategies, reaction mechanisms, key intermediates, and several novel ligands and chiral gold salts.