Premium
Front Cover: Tunable Performance of Manganese Oxide Nanostructures as MRI Contrast Agents (Chem. Eur. J. 6/2018)
Author(s) -
BañobreLópez Manuel,
GarcíaHevia Lorena,
Cerqueira M. Fatima,
Rivadulla Francisco,
Gallo Juan
Publication year - 2018
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201705893
Subject(s) - manganese , manganese oxide , nanostructure , contrast (vision) , oxide , nanotechnology , materials science , contrast enhancement , redox , chemistry , combinatorial chemistry , nuclear magnetic resonance , computer science , physics , magnetic resonance imaging , inorganic chemistry , medicine , radiology , artificial intelligence , organic chemistry
A simple one‐pot method was used to prepare a range of manganese oxide nanostructures of different nature (MnO, MnO 2 , Mn 3 O 4 ) and shape, to be explored as MRI contrast agents. The availability of redox states of Mn required a special combination of techniques to unequivocally identify the phase of the materials. From the imaging point of view, while MnO nanostructures behave as classic T 1 contrast enhancers, MnO 2 nanourchins emerge as efficient responsive probes, superior to MnO 2 nanosheets, able to increase their signal over 140‐fold upon activation under oncology‐relevant conditions. More information can be found in the Full Paper by M. Bañobre‐López, J. Gallo et al. on page 1295.