Co III ‐Catalyzed Isonitrile Insertion/Acyl Group Migration Between C−H and N−H bonds of Arylamides | Zendy

Kalsi Deepti | Zendy; Barsu Nagaraju | Zendy; Sundararaju Basker | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Co III ‐Catalyzed Isonitrile Insertion/Acyl Group Migration Between C−H and N−H bonds of Arylamides

Author(s) -

Kalsi Deepti,

Barsu Nagaraju,

Sundararaju Basker

Publication year - 2018

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201705710

Subject(s) - chemistry , intramolecular force , catalysis , medicinal chemistry , chelation , cobalt , stereochemistry , alcohol , migratory insertion , organic chemistry

A general efficient and site‐selective cobalt‐catalyzed insertion of isonitrile into C−H and N−H bonds of arylamides through C−H bond activation and alcohol assisted intramolecular trans ‐amidation is demonstrated. This straightforward approach overcomes the limitation by the presence of strongly chelating groups. Isolation of Co III ‐isonitrile complex B has been achieved for the first time to understand the reaction mechanism.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research