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Heterobimetallic Complexes for Theranostic Applications
Author(s) -
FernándezMoreira Vanesa,
Gimeno M. Concepción
Publication year - 2018
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201705335
Subject(s) - biodistribution , nanotechnology , mechanism (biology) , imaging agent , computer science , chemistry , materials science , biology , physics , microbiology and biotechnology , biochemistry , quantum mechanics , in vivo , in vitro
The design of more efficient anticancer drugs requires a deeper understanding of their biodistribution and mechanism of action. Cell imaging agents could help to gain insight into biological processes and, consequently, the best strategy for attaining suitable scaffolds in which both biological and imaging properties are maximized. A new concept arises in this field that is the combination of two metal fragments as collaborative partners to provide the precise emissive properties to visualize the cell as well as the optimum cytotoxic activity to build more potent and selective chemotherapeutic agents.