C−F Bond Activation by Silylium Cation/Phosphine Frustrated Lewis Pairs: Mono‐Hydrodefluorination of PhCF 3 , PhCF 2 H and Ph 2 CF 2 | Zendy

Mallov Ian | Zendy; Ruddy Adam J. | Zendy; Zhu Hui | Zendy; Grimme Stefan | Zendy; Stephan Douglas W. | Zendy

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C−F Bond Activation by Silylium Cation/Phosphine Frustrated Lewis Pairs: Mono‐Hydrodefluorination of PhCF 3 , PhCF 2 H and Ph 2 CF 2

Author(s) -

Mallov Ian,

Ruddy Adam J.,

Zhu Hui,

Grimme Stefan,

Stephan Douglas W.

Publication year - 2017

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201705276

Subject(s) - phosphine , chemistry , aryl , frustrated lewis pair , lewis acids and bases , polymer chemistry , base (topology) , phosphine oxide , intermolecular force , medicinal chemistry , organic chemistry , alkyl , molecule , catalysis , mathematical analysis , mathematics

Single defluorination of aryl polyfluoromethyl functionalities is achieved by both intra‐ and intermolecular silylium cation/phosphine Lewis pairs. Phosphine‐captured aryl fluoromethyl cations are then treated with Brønsted base to complete the first mono‐hydrodefluorinations of PhCF 3 , Ph 2 CF 2 , and PhCF 2 .

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