Premium
Chemical and Enzymatic Strategies for Bacterial and Mammalian Cell Surface Engineering
Author(s) -
Bi Xiaobao,
Yin Juan,
Chen Guanbang Ashley,
Liu ChuanFa
Publication year - 2018
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201705049
Subject(s) - cell , surface engineering , synthetic biology , nanotechnology , surface modification , biochemical engineering , chemistry , biology , computational biology , materials science , biochemistry , engineering
The cell surface serves important functions such as the regulation of cell‐cell and cell‐environment interactions. The understanding and manipulation of the cell surface is important for a wide range of fundamental studies of cellular behavior and for biotechnological and medical applications. With the rapid advance of biology, chemistry and materials science, many strategies have been developed for the functionalization of bacterial and mammalian cell surfaces. Here, we review the recent development of chemical and enzymatic approaches to cell surface engineering with particular emphasis on discussing the advantages and limitations of each of these strategies.