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Cytotoxicity of Group 5 Transition Metal Ditellurides (MTe 2 ; M=V, Nb, Ta)
Author(s) -
Chia Hui Ling,
Latiff Naziah Mohamad,
Sofer Zdenĕk,
Pumera Martin
Publication year - 2018
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201704316
Subject(s) - transition metal , cytotoxicity , chemistry , nanotechnology , metal , materials science , organic chemistry , in vitro , biochemistry , catalysis
Much research effort has been put in to study layered compounds with transition metal dichalcogenides (TMDs) being one of the most studied compounds. Due to their extraordinary properties such as excellent electrochemical properties, tuneable band gaps, and low shear resistance due to weak van der Waals interactions between layers, TMDs have been found to have wide applications such as electrocatalysts for hydrogen evolution reactions, supercapacitors, biosensors, field‐effect transistors (FETs), photovoltaics, and lubricant additives. In very recent years, Group 5 transition metal ditellurides have received an immense amount of research attention. However to date, little has been known of the potential toxicities posed by these materials. As such, we conducted the cytotoxicity study by incubating various concentrations of the Group 5 transition metal ditellurides (MTe 2 ; M=V, Nb, Ta) with human lung carcinoma epithelial A549 cells for 24 hours and the remaining cell viabilities after treatment was measured. Our findings indicate that VTe 2 is highly toxic whereas NbTe 2 and TaTe 2 are deemed to exhibit mild toxicities. This study constitutes an exemplary first step towards the understanding of the Group 5 transition metal ditellurides’ toxicity effects in preparation for their possible future commercialisation.