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Front Cover: Design and Fabrication of Temperature‐Sensitive Nanogels with Controlled Drug Release Properties for Enhanced Photothermal Sterilization (Chem. Eur. J. 72/2017)
Author(s) -
Li Luoyuan,
Fu Limin,
Ai Xicheng,
Zhang Jianping,
Zhou Jing
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201704202
Subject(s) - photothermal therapy , poly(n isopropylacrylamide) , materials science , polymerization , photothermal effect , pedot:pss , nanoparticle , precipitation polymerization , nanotechnology , drug delivery , curcumin , radical polymerization , chemical engineering , chemistry , polymer , layer (electronics) , composite material , copolymer , engineering , biochemistry
Designed PEDOT@PNIPAAm nanogels were fabricated by using temperature‐sensitive hydrogel [poly( N ‐isopropylacrylamide) (PNIPAAm)] to encapsulate poly(3,4‐ethylenedioxythiophene) (PEDOT) nanoparticles (photothermal agents) and curcumin through a reformative precipitation polymerization. When triggered by near‐infrared light (NIR), the nanogels exhibited high photothermal conversion efficiency, and excellent temperature‐sensitive effects. The light induced temperature increase can weaken the interaction between the networks of PNIPAAm and curcumin to exert antioxidant and antibacterial performances. More information can be found in the Full Paper by L. Fu, J. Zhou et al. on page 18180.