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Unprecedented One‐Pot Reaction towards Chiral, Non‐Racemic Copper(I) Complexes of [2.2]Paracyclophane‐Based P,N ‐Ligands
Author(s) -
Braun Carolin,
Nieger Martin,
Bräse Stefan
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201704115
Subject(s) - enantiopure drug , phosphine , ligand (biochemistry) , pyridine , copper , chemistry , palladium , transition metal , combinatorial chemistry , stereochemistry , medicinal chemistry , enantioselective synthesis , catalysis , organic chemistry , receptor , biochemistry
Herein, we report a simple one‐pot route to enantiopure copper(I) complexes featuring a unique [2.2]paracyclophane‐based P,N ‐ligand system. Phosphine and pyridine moieties can be varied allowing the modular synthesis of these rigid and stable [2.2]paracyclophane‐based P,N ‐ligands. These P,N ‐ligands are a new ligand class for different transition‐metal complexes, which is shown exemplarily for palladium(II).