Premium
Front Cover: N ‐Methyl Inversion and Accurate Equilibrium Structures in Alkaloids: Pseudopelletierine (Chem. Eur. J. 65/2017)
Author(s) -
VallejoLópez Montserrat,
Écija Patricia,
Vogt Natalja,
Demaison Jean,
Lesarri Alberto,
Basterretxea Francisco J.,
Cocinero Emilio J.
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201704113
Subject(s) - tropane , conformational isomerism , stereochemistry , chemistry , molecule , organic chemistry
Pseudopelletierine is a natural compound belonging to the tropane alkaloids family which has different pharmacological properties. Here, we address the structure of the two conformers unambiguously identified in the gas phase. The possible connections of the axial/equatorial (ax/eq) isomerism with its biological role have motivated the study of the ax/eq rates in pseudopelletierine and it has been compared to the rest of the tropane alkaloids. More information can be found in the Full Paper by N. Vogt, A. Lesarri, E. J. Cocinero et al. on page 16491.