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Chiral Inactivation: An Old Phenomenon with a New Twist
Author(s) -
Raskatov Jevgenij A.
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201703869
Subject(s) - enantiomer , chirality (physics) , twist , bioorganic chemistry , molecule , chemistry , combinatorial chemistry , catalysis , stereochemistry , computational chemistry , nanotechnology , materials science , organic chemistry , physics , chiral symmetry , mathematics , particle physics , geometry , nambu–jona lasinio model , enzyme , quark
Abstract Mixing of enantiomers of chiral molecules can have remarkable effects on the properties of their higher order assemblies. This, in turn, may have profound impact on both structural and functional outcomes, and has been noted across a wide range of contexts. This account presents key examples from organic, organometallic and bioorganic molecular sciences and showcases that, in disciplines as distinct as asymmetric catalysis and racemic protein crystallography, there is a fundamental way in which enantiomers differ from racemates.