Asymmetric Alkynylation of β‐Ketoesters and Naphthols Promoted by New Chiral Biphenylic Iodanes | Zendy

Companys Simon | Zendy; Peixoto Philippe A. | Zendy; Bosset Cyril | Zendy; Chassaing Stefan | Zendy; Miqueu Karinne | Zendy; Sotiropoulos JeanMarc | Zendy; Pouységu Laurent | Zendy; Quideau Stéphane | Zendy

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Asymmetric Alkynylation of β‐Ketoesters and Naphthols Promoted by New Chiral Biphenylic Iodanes

Author(s) -

Companys Simon,

Peixoto Philippe A.,

Bosset Cyril,

Chassaing Stefan,

Miqueu Karinne,

Sotiropoulos JeanMarc,

Pouységu Laurent,

Quideau Stéphane

Publication year - 2017

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201703238

Subject(s) - alkynylation , reagent , enantioselective synthesis , enantiomer , enantiomeric excess , chemistry , combinatorial chemistry , organic chemistry , catalysis

The preparation of new chiral biphenylic λ 3 ‐iodane reagents bearing transferable alkynyl ligands is described. These reagents transfer their carbon‐based ligands onto β‐ketoesters with an enantiomeric excess ( ee ) up to 68 %, and most remarkably, enable the dearomative alkynylation of naphthols in good to high yields up to 84 % ee .

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