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Cover Feature: Aggregation‐Induced Emission (AIE) Fluorophore Exhibits a Highly Ratiometric Fluorescent Response to Zn 2+ in vitro and in Human Liver Cancer Cells (Chem. Eur. J. 53/2017)
Author(s) -
Mehdi Hassan,
Gong Weitao,
Guo Huimin,
Watkinson Michael,
Ma Hua,
Wajahat Ali,
Ning Guiling
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201703192
Subject(s) - fluorophore , fluorescence , confocal microscopy , chemistry , confocal , intracellular , in vitro , biophysics , cancer cell , detection limit , human liver , microscopy , cancer , biochemistry , microbiology and biotechnology , biology , optics , medicine , pathology , chromatography , physics , genetics
A new AIE‐active fluorophore that exhibits a rapid and highly selective ratiometric response to Zn 2+ with a limit of detection (LOD) up to 2.6 n m is reported. Furthermore, the fluorophore was successfully applied in ratiometric imaging of intracellular Zn 2+ in human hepatoma cancer cells by fluorescent confocal microscopy. More information can be found in the Full Paper by W. Gong, M. Watkinson, G. Ning et al. on page 13067.