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Cover Feature: Tunable Ligand Effects on Ruthenium Catalyst Activity for Selectively Preparing Imines or Amides by Dehydrogenative Coupling Reactions of Alcohols and Amines (Chem. Eur. J. 52/2017)
Author(s) -
Higuchi Takafumi,
Tagawa Risa,
Iimuro Atsuhiro,
Akiyama Shoko,
Nagae Haruki,
Mashima Kazushi
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201702953
Subject(s) - ruthenium , chemistry , ligand (biochemistry) , catalysis , denticity , combinatorial chemistry , coupling reaction , organic chemistry , metal , biochemistry , receptor
Ligand‐controlled selective dehydrogenative coupling reactions of alcohols and amines were achieved by using ruthenium complexes bearing P−N bidentate ligands with zinc salts. A wide variety of alcohols and amines were used in the present systems to obtain the corresponding imines and amides. In addition, a ruthenium complex as the catalyst precursor was successfully isolated and reaction mechanisms are proposed based on experiments, including a time‐course study, Hammett plot, and measurements of the kinetic isotope effect. More information can be found in the Full Paper by K. Mashima et al. on page 12795.