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Electron Transfer of Cytochrome c on Surface‐Enhanced Raman Scattering–Active Substrates: Material Dependence and Biocompatibility
Author(s) -
Li Junbo,
Cheng Weina,
Wang Xiaolei,
Zhang Haijing,
Jin Jing,
Ji Wei,
Han Xiao Xia,
Zhao Bing
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201702307
Subject(s) - raman spectroscopy , electron transfer , raman scattering , biocompatibility , transition metal , photochemistry , materials science , surface enhanced raman spectroscopy , nanoparticle , chemistry , nanotechnology , organic chemistry , catalysis , optics , physics
Surface‐enhanced Raman spectroscopy (SERS) represents a powerful approach for studying the structure and reaction of proteins in fundamental and applied sciences. The surface properties of SERS‐active materials determine important parameters such as Raman enhancement ability, biocompatibility, and electronic communication between supports and proteins. Here, electron transfer (ET) of Cyt c on noble metals and transition metals is investigated by SERS spectroscopy. The results here indicate that the ET occurs from the reduced state of Cyt c to silver substrate, depending on the laser wavelengths. Nickel and cobalt can directly transfer electrons to the oxidized state of Cyt c , which enables a reductive activity of these transition metal nanoparticles (NPs). This study demonstrates the role of transition metals as electron donors for Cyt c and has proved that the charge transfer theory for SERS is applicable for explanation of the ET between Cyt c and Ag NPs.