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Visible‐Light‐Mediated Dual Decarboxylative Coupling of Redox‐Active Esters with α,β‐Unsaturated Carboxylic Acids
Author(s) -
Zhang JinJiang,
Yang JunCheng,
Guo LiNa,
Duan XinHua
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201702200
Subject(s) - decarboxylation , chemistry , redox , carboxylic acid , functional group , visible spectrum , alkyl , carboxylate , organic chemistry , combinatorial chemistry , photochemistry , catalysis , materials science , optoelectronics , polymer
An efficient visible‐light‐induced decarboxylative coupling between α,β‐unsaturated carboxylic acids and alkyl N ‐hydroxyphthalimide esters has been developed. A wide range of redox‐active esters derived from aliphatic carboxylic acids (1°, 2° and 3°) proved viable in this dual decarboxylation process, affording a broad scope of substituted alkenes in moderate to excellent yields with good E / Z selectivities. This redox‐neutral procedure was highlighted by its mild conditions, operational simplicity, easy accessibility of carboxylic acids, and excellent functional‐group tolerance.