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Vinylpyridines as Building Blocks for the Photocatalyzed Synthesis of Alkylpyridines
Author(s) -
Capaldo Luca,
Fagi Maurizio,
Ravelli Davide
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201701346
Subject(s) - photocatalysis , chemistry , salt (chemistry) , simple (philosophy) , combinatorial chemistry , organic chemistry , catalysis , philosophy , epistemology
The photocatalyzed addition of several hydrogen donors (ethers, aldehydes, alkanes, amides) onto vinylpyridines was achieved. This approach provided access to alkylpyridines, which are important building blocks for the preparation of compounds with biological activity. The strategy was very simple and straightforward because it required only a small amount of a cheap decatungstate salt as photocatalyst. As an added advantage, the reaction could be performed under sunlight irradiation as well as under flow conditions.