Premium
Inside Back Cover: On the Way to a Trisanionic {Cu 3 O 2 } Core for Oxidase Catalysis: Evidence of an Asymmetric Trinuclear Precursor Stabilized by Perfluoropinacolate Ligands (Chem. Eur. J. 34/2017)
Author(s) -
Hannigan Steven F.,
Arnoff Amanda I.,
Neville Sarah E.,
Lum June S.,
Golen James A.,
Rheingold Arnold L.,
Orth Nicole,
IvanovićBurmazović Ivana,
Liebhäuser Patricia,
Rösener Thomas,
Stanek Julia,
Hoffmann Alexander,
HerresPawlis Sonja,
Doerrer Linda H.
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201701242
Subject(s) - catalysis , chemistry , cover (algebra) , copper , core (optical fiber) , multicopper oxidase , spectroscopy , density functional theory , stereochemistry , crystallography , computational chemistry , materials science , organic chemistry , enzyme , physics , mechanical engineering , engineering , composite material , laccase , quantum mechanics
Side‐by‐side : Two trinuclear copper‐dioxygen species have been characterized by UV/Vis stopped‐flow spectroscopy in solution—an asymmetric and a symmetric one being the final product of the oxygenation. For the first time, these rare biomimetic species could be stabilized by dianionic ligands by using perfluoropinacolate. The asymmetric trinuclear core is a true model for the active site of multicopper oxidases. Density functional calculations yielded further insights into the electronic structure and catalytic measurements prove the oxidation capability of the symmetric trinuclear core. More information can be found in the Full Paper by S. Herres‐Pawlis, L. H. Doerrer et al. on page 8212.