Premium
Gold(I)‐Catalyzed Cycloisomerization of ortho ‐(Propargyloxy)arenemethylenecyclopropanes Controlled by Adjacent Substituents at Aromatic Rings
Author(s) -
Fang Wei,
Wei Yin,
Tang XiangYing,
Shi Min
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201700600
Subject(s) - cycloisomerization , catalysis , chemistry , aromaticity , medicinal chemistry , stereochemistry , organic chemistry , molecule
Gold(I)‐catalyzed cycloisomerization of ortho ‐(propargyloxy)arenemethylenecyclopropanes afforded two different types of products, that is, products of methylenecyclopropane migration and cycloisomerization products of the methylenecyclopropane moiety, controlled jointly by electronic and steric effects of the adjacent substituents. Furthermore, the corresponding cycloisomerization products could be also produced in an enantiomerically enriched manner.