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Helical Polyisocyanopeptides as Lyotropic Liquid Crystals for Measuring Residual Dipolar Couplings
Author(s) -
Li GaoWei,
Cao JiangMing,
Zong Wen,
Hu Li,
Hu MaoLin,
Lei Xinxiang,
Sun Han,
Tan Ren Xiang
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201700539
Subject(s) - residual dipolar coupling , lyotropic , dipole , residual , liquid crystal , biomolecule , molecule , chemical physics , crystallography , chemistry , lyotropic liquid crystal , materials science , nuclear magnetic resonance , nanotechnology , liquid crystalline , organic chemistry , physics , computer science , optoelectronics , algorithm
Residual dipolar couplings (RDC) emerged to be an important structural parameter for organic and biomolecules. Herein, a new helical polyisocyanopeptide ( l,l ‐PIAF‐OBn) that forms lyotropic liquid crystals (LLC) in CDCl 3 is proposed as a novel weakly orienting medium for acquiring residual dipolar couplings (RDCs) of organic molecules. We demonstrate its application for the structural elucidation of strychnine and triptolide.