Premium
Zn 2+ ‐Ion Sensing by Fluorescent Schiff Base Calix[4]arene Macrocycles
Author(s) -
Ullmann Steve,
Schnorr René,
Handke Marcel,
Laube Christian,
Abel Bernd,
Matysik Jörg,
Findeisen Matthias,
Rüger Robert,
Heine Thomas,
Kersting Berthold
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201700253
Subject(s) - chemistry , schiff base , fluorescence , electrospray ionization , ligand (biochemistry) , proton nmr , calixarene , mass spectrometry , metal ions in aqueous solution , fluorescence spectroscopy , quenching (fluorescence) , divalent , metal , crystallography , ion , stereochemistry , molecule , organic chemistry , biochemistry , physics , receptor , chromatography , quantum mechanics
A macrocyclic ligand (H 2 L) containing two o,o′ ‐bis(iminomethyl)phenol and two calix[4]arene head units has been synthesized and its coordination chemistry towards divalent Ni and Zn investigated. The new macrocycle forms complexes of composition [ML] (M=Zn, M=Ni) and [ZnL(py) 2 ], which were characterized by elemental analysis; IR, UV/Vis, and NMR spectroscopy; electrospray ionization mass spectrometry (ESI‐MS); and X‐ray crystallography (for [ZnL(py) 2 ] and [NiL]). H 2 L allows the sensitive optical detection of Zn 2+ among a series of biologically relevant metal ions by a dual fluorescence enhancement/quenching effect in solution. The fluorescence intensity of the macrocycle increases by a factor of ten in the presence of Zn 2+ with a detection limit in the lower nanomolar region.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom