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Inside Back Cover: Protein Adsorption Switch Constructed by a Pillar[5]arene‐Based Host–Guest Interaction (Chem. Eur. J. 3/2016)
Author(s) -
Xiao Xuan,
Nie Guanrong,
Zhang Xiaoyan,
Tian Demei,
Li Haibing
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201680303
Subject(s) - adsorption , pillar , substrate (aquarium) , drug delivery , contact angle , nanotechnology , protein adsorption , chemistry , materials science , silicon , adipic acid , biosensor , combinatorial chemistry , polymer chemistry , optoelectronics , organic chemistry , oceanography , structural engineering , composite material , engineering , geology
The interfacial properties of solid substrates are of importance for protein adsorption. A reversible protein adsorption switch based on the host–guest interaction of the butoxy pillar[5]arene and adipic acid is reported. Through the detection of the contact angle, AFM and luminoscope measurements on the silicon substrate, the intelligent protein switch was found to exhibit excellent adsorptivity for BSA and switch performance by pH regulation. This system holds the possibility for wide applications in the production of new biosensors, immunological tests, and drug delivery. More information can be found in the Full Paper by H. Li et al. on page 941 ff.