Premium
Cobalt‐Catalyzed Regioselective Borylation of Arenes: N‐Heterocyclic Silylene as an Electron Donor in the Metal‐Mediated Activation of C−H Bonds
Author(s) -
Ren Hailong,
Zhou YuPeng,
Bai Yunping,
Cui Chunming,
Driess Matthias
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201605937
Subject(s) - borylation , silylene , regioselectivity , chemistry , catalysis , pincer movement , cobalt , pyridine , combinatorial chemistry , ligand (biochemistry) , medicinal chemistry , photochemistry , aryl , organic chemistry , silicon , alkyl , biochemistry , receptor
C−H Borylation of arenes has been a subject of great interest recently because of its atom‐economy and the wide applicability of borylated products in value‐added synthesis. A new bis(silylene)cobalt(II) complex bearing a bis( N ‐heterocyclic silylene)‐pyridine pincer ligand (SiNSi) has been synthesized and structurally characterized. It enabled the regioselective catalytic C−H borylation of pyridines, furans, and fluorinated arenes. Notably, it exhibited complementary regioselectivity for the borylation of fluorinated arenes compared to previously known catalytic systems, demonstrating that N‐heterocyclic silylene donors have enormous potential in metal‐catalyzed catalytic applications.