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A Photoregulated DNA‐Based Rotary System and Direct Observation of Its Rotational Movement
Author(s) -
Yang Yangyang,
Tashiro Ryu,
Suzuki Yuki,
Emura Tomoko,
Hidaka Kumi,
Sugiyama Hiroshi,
Endo Masayuki
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201605616
Subject(s) - tile , rotor (electric) , materials science , ultraviolet light , nanotechnology , rotation (mathematics) , nanometre , dna , rotation around a fixed axis , dna origami , optoelectronics , optics , chemistry , nanostructure , physics , computer science , classical mechanics , biochemistry , quantum mechanics , artificial intelligence , composite material
Various DNA‐based nanodevices have been developed on the nanometer scale using light as regulation input. However, the programmed controllability is still a major challenge for these artificial nanodevices. Herein, we demonstrate a rotary DNA nanostructure in which the rotations are controlled by light. A bar‐shaped DNA rotor, fabricated as a stiff double‐crossover molecule, was placed on the top of a rectangular DNA tile. The photoresponsive oligonucleotides modified with azobenzenes were employed as switching motifs to release/trap the rotor at specific angular position on DNA tile by switching photoirradiations between ultraviolet and visible light. As a result, two reconfigurable states (perpendicular and parallel) of rotor were obtained, in which the angular changes were characterized by AFM and fluorescence quenching assays. Moreover, the reversible rotary motions during the photoirradiation were directly visualized on the DNA tile surface in a nanometer‐scale precision using a second‐scale scanning of the high‐speed AFM.