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Manganese‐Catalyzed Hydrogenation of Esters to Alcohols
Author(s) -
EspinosaJalapa Noel Angel,
Nerush Alexander,
Shimon Linda J. W.,
Leitus Gregory,
Avram Liat,
BenDavid Yehoshoa,
Milstein David
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201604991
Subject(s) - catalysis , manganese , chemistry , homogeneous , metal , organic chemistry , homogeneous catalysis , noyori asymmetric hydrogenation , reaction mechanism , reaction conditions , catalytic hydrogenation , ruthenium , physics , thermodynamics
Homogeneous catalytic hydrogenation of esters to alcohols is an industrially important, environmentally benign reaction. While precious metal‐based catalysts for this reaction are now well known, only very few catalysts based on first‐row metal complexes were reported. Here we present the hydrogenation of esters catalyzed by a complex of earth‐abundant manganese. The reaction proceeds under mild conditions and insight into the mechanism is provided based on an NMR study and the synthesis of novel Mn complexes postulated as intermediates.